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FAQ (FREQUENTLY ASKED QUESTIONS)

Do I need a request form from my doctor for SANCO testing?

We recommend the SANCO Test to be ordered by a physician. Please check with the chosen local SANCO provider, whether the doctor is on the spot or talk about the test with your doctor.

When is the earliest possible time for performing SANCO prenatal test?

We recommend performing the SANCO Test between 10 and 24 weeks of pregnancy. There are no contraindications for the SANCO test in the advanced pregnancy (even after the 24th week of pregnancy), however, the patient should be aware that after obtaining a bad/unfavourable test result, she should decide on invasive testing to verify the risk and in advanced pregnancy it is not always possible.

What does the visit and blood draw look like? Do I have to be specially prepared for it?

The patient should have an ultrasound result of her current pregnancy or perform an ultrasound during the SANCO appointment. If other screening tests or pregnancy karyotype tests were performed, please take the results of these tests with you. You need to make sure how much the visit will cost in advance and what it includes, and whether you need to schedule an appointment.
SANCO is a genetic test, so its performance should be preceded by consultation with a specialist in genetics or gynecology and obstetrics. Following issues should be discussed during the appointment: the patient's procreative history, genetic diseases in the family and the results concerning the current pregnancy. Before testing the patient should become familiar with all the conditions and limitations of the test, and sign a Consent Form.
The procedure is analogous to taking blood for morphological testing. However, the test tube differs (it has a camo plug), because the blood cells have to be protected against disintegration and contamination of the cell-free DNA. The analysis itself requires 10 ml of blood sample. The testing doesn’t require fasting. As before the usual blood draw, it is good to drink extra liquid.

How is blood collected for the test?

10 ml of venous blood are collected. The procedure is analogous to taking blood for morphological testing. However, the test tube differs (it has a camo plug), because the blood cells have to be protected against disintegration and contamination of the cell-free DNA. The analysis itself requires 10 ml of blood sample. The testing doesn’t require fasting. As before the usual blood draw, it is good to drink extra liquid. 

Is it true that the RHD Test can be performed with the SANCO Prenatal Test?

YES, it is possible, if the patient is Rh- and has no anti-D antibodies. Both tests are ordered on one form, two blood tubes are taken, and the price of the child's RHD testing is lower than when the RHD Test is ordered separately. 

How long would I wait for the test result?

The standard issuing time is a few days, and the maximum waiting timeis 5 business days from the date of delivery of the sample to the Genomed SA Laboratory (Warsaw, Poland). Due to the sensitive data security, Genomed employees do not provide any information about the progress and results of the testing by e-mail or phone. The SANCO Test result can be picked up at the clinic/facility, where the blood donation has been drawn performed and is available on the dedicated on-line platform immediately after it has been issued. Any information about the ongoing testing should be provided to the patient by the local SANCO provider. If you perform testing directly at Genomed, you will be informed by Genomed’s employees that you may pick up your result.

How many deletion/duplication syndromes are detected in the SANCO Test?

Exactly that amount as in the amniotic fluid testing (karyotype) from amniocentesis. On the "TEST RANGE" page, you can find several examples of common and known deletion syndromes, such as 1p36 deletion, Cri-du-chat syndrome (5p), 12p duplication, 16p11.2-p12.2 deletion, Pallister-Killian syndrome (12p isochromosome), 16p11.2-p12.2 duplication, cat eye syndrome (22pter-22q11 tetrasomy), 2q33.1 deletion. SANCO Test has the potential to "catch" any defect, both deletion and duplication larger than7 million letters of DNA. There are an infinite number of such possible conditions! By browsing only one database  (Decipher v11.2), there are over 430 different aberrations possible to be detected in SANCO and thousands of described patients.

When the SANCO Test is not recommended?

We don’t recommend to perform the SANCO Test within 12 months after a blood transfusion, after bone marrow or organ transplantation, after stem cell therapy, immediately after vaccination with partner lymphocytes and before 8 weeks from fetal death in a multiple pregnancy, on condition that death occurred no later than at 8th week of pregnancy. Most chromosomal aberrations in a pregnant woman are also a contraindication to the SANCO testing and each case should be reported to the physician. It has been observed that certain diseases of the immune and hematopoietic system make it difficult to obtain the test result. Sometimes, also for reasons other than those indicated above, the SANCO Test is not the right choice. That is why we recommend consultation each time before performing the test.

Can any medication or infection falsify the SANCO Test result?

None of medicines tested was an impediment to SANCO, cold or other common conditions does not interfere. On the other hand, ongoing cancer and active autoimmune disease may cause the test to be inapplicable.

I'm obese and I've heard that the cell-free fetal DNA test may fail. Is there any point to perform a SANCO Test?

SANCO Test is a particularly good choice among all available NIPT tests, because it requires the least fetal DNA, even as low as 1%.