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GENOME-WIDE PRENATAL TEST

SANCO is a non-invasive prenatal genetic test that detects fetal abnormalities.

SANCO test analyses cell-free DNA from a maternal blood sample (mixture of fetal and maternal DNA) to screen for chromosomal conditions, including trisomy 21 (Down syndrome).

The test assesses the whole fetal genome, that is all 23 pairs of chromosomes, and the fetal sex.

THE ADVANTAGES OF THE SANCO TEST

GENOME-WIDE

Assessment of changes in the number and structure of all 23 pairs of chromosomes

SIMPLE

A small sample of maternal blood is sufficient

FAST

Performed in Poland
Maximum 5 business days turnaround

EFFECTIVE

The lowest test failure rate on the market

ACCURATE

>99% sensitivity

RELIABLE

CE-IVD certificate for the entire process.
Patient consent form and report available in English language

 

TEST RANGE

Examines the entire genome of the fetus
Detects the trisomies and monosomies of all 23 chromosome pairs
Allows to determine the risk of mosaicism
Detects deletion and duplication syndromes
Optional fetal RhD determination
Enables fetal sex determination

WHY TO CHOOSE THE SANCO PRENATAL TEST?
- TEST INDICATIONS

Maternal age 35 years or older
Anxiety of the mother
Positivity for first or second trimester screening tests
Prior pregnancy with chromosomal abnormalities
Contraindications for invasive prenatal testing

Learn more about the most important indications to perform non-invasive prenatal SANCO Test

TECHNOLOGY

SANCO test is based on the VeriSeq technology from Illumina Inc. (USA) - the sequencing solution world leader. The method helps to maintain high effectiveness of the testing, even at 1% of fetal fraction (the concentration of placental cfDNA in plasma). No result was observed only for less than 1% of tests performed.

THE SANCO TEST COMPARED WITH OTHER PRENATAL APPROACHES

Traditional screenings, like ultrasound or first trimester combined (PAPP-A) test, in comparison with the SANCO Test, have lower sensitivity and a 20 times higher false positive rate. Invasive methods, such as amniocentesis, give a diagnostic result, but they carry 0,1-2% risk of miscarriage and time to get the result is almost three times longer than provided in the SANCO Test. In the invasive testings, similarly as in the SANCO Test, all 23 pairs of fetal chromosomes are analyzed for their correct number and structure. Both types of tests can detect deletion syndromes covering at least 7 Mbp. This resolution is similar to the karyotype amniotic fluid testing (so-called amniocentesis).

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FAQ (FREQUENTLY ASKED QUESTIONS)

Browse the list of frequently asked questions raised by our patients. If you have questions that you have not found an answer to - write to us or call us!





Do I need a request form from my doctor for SANCO testing?

We recommend the SANCO Test to be ordered by a physician. Please check with the chosen local SANCO provider, whether the doctor is on the spot or talk about the test with your doctor.

Which version of the SANCO should I choose?

The SANCO Test detects trisomies and monosomies of all 23 chromosome pairs as well as deletion and duplication syndromes of at least 7 million base pairs. Thanks to this, the scope and resolution of the test is comparable to the karyotype of amniotic fluid testing (from amniocentesis).
The SANCO plus Test, offered by Genomed only in the Polish territory, is designated only for specific cases. It is the right choice for patients who want to perform tests for 5 selected deletion syndromes. Some deletions detected in the SANCO plus Test may be less than 7 million base pairs and for this reason will not be detected in the SANCO test (22q11, 4p16.3 and 15q11,2 deletions). In other cases we recommend performing the SANCO Test.

How much does the SANCO Test cost?

We provide two options of the test: SANCO and SANCO PLUS. SANCO PLUS is more expensive and turnaround time is longer.
The prices available for patients in the Genomed Health Care Centre: 2,000 PLN (SANCO) and 2,500 PLN (SANCO PLUS). This price includes a short consultation prior the test.
Genomed does not monitor the prices of the SANCO Test in the partner facilities. Prices may vary between facilities/clinics in Poland. Sometimes this is due to the fact that the price includes a visit or an ultrasound examination.

When is the earliest possible time for performing SANCO prenatal test?

We recommend performing the SANCO Test between 10 and 24 weeks of pregnancy. There are no contraindications for the SANCO test in the advanced pregnancy (even after the 24th week of pregnancy), however, the patient should be aware that after obtaining a bad/unfavourable test result, she should decide on invasive testing to verify the risk and in advanced pregnancy it is not always possible.